KMID : 0857020100250020203
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Kosin Medical Journal 2010 Volume.25 No. 2 p.203 ~ p.207
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Active Tuberculosis Occurred in Rheumatoid Arthritis Patient Who is Treated with Etanercept after Antituberculosis Chemoprophylaxis with Rifampin
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Lee Hae-Won
Lee Tae-Hwa Kim Geun-Tae
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Abstract
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Tuberculosis infection is a rare but important side effect of anti-tumor necrosis factor agents that are widely used in the treatment of rheumatoid arthritis. A 63-year-old woman with rheumatoid arthritis who had been treated with etanercept visited the hospital because of polyarthralgia and right neck pain. Before use of etanercept, she was treated for latent tuberculosis. When the patient came to the hospital, she had no respiratory symptoms. But, we found abnormal findings in regularly follow-up chest x-ray. She was diagnosed as reactivation of latent tuberculosis by bronchoscopy. After stopping the etanercept, she has been treated with anti-tuberculosis agents, disease modifying anti-rheumatic drugs, and intra-articular steroid injection. We report here on this unusual case along with a review of the relevant literature.
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KEYWORD
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latent tuberculosis, rheumatoid arthritis
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