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KMID : 0857020100250020203
Kosin Medical Journal
2010 Volume.25 No. 2 p.203 ~ p.207
Active Tuberculosis Occurred in Rheumatoid Arthritis Patient Who is Treated with Etanercept after Antituberculosis Chemoprophylaxis with Rifampin
Lee Hae-Won

Lee Tae-Hwa
Kim Geun-Tae
Abstract
Tuberculosis infection is a rare but important side effect of anti-tumor necrosis factor agents that are widely used in the treatment of rheumatoid arthritis. A 63-year-old woman with rheumatoid arthritis who had been treated with etanercept visited the hospital because of polyarthralgia and right neck pain. Before use of etanercept, she was treated for latent tuberculosis. When the patient came to the hospital, she had no respiratory symptoms. But, we found abnormal findings in regularly follow-up chest x-ray. She was diagnosed as reactivation of latent tuberculosis by bronchoscopy. After stopping the etanercept, she has been treated with anti-tuberculosis agents, disease modifying anti-rheumatic drugs, and intra-articular steroid injection. We report here on this unusual case along with a review of the relevant literature.
KEYWORD
latent tuberculosis, rheumatoid arthritis
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